Diabetes is a disease caused as a result of chronic metabolic dysfunction of glucose, a principal energy source of the body cells. Glucose is obtained from dietary carbohydrates and synthesized in the body from a substrate of fatty acids and amino acids. The major and most important hormone that is required for glucose metabolism is insulin, which is produced and secreted from pancreatic islets β cells. Due to the lack of insulin secretion and the increase of insulin resistance the blood glucose rises and causes diabetes.
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